Cholera in 2025: A Study of the Disease and Its Causes and Prevention

Cholera in 2025: A Study of the Disease and Its Causes and Prevention

Cholera remains an active public health threat in 2025 as long as there is no clean water and sanitation. It is an infectious disease caused by the bacterium Vibrio cholerae and is spread by contaminated food and drinking water. Cholera is preventable and treatable and still causes disease and death among the most vulnerable populations globally.


 Causes and Transmission

The major cause of cholera is the ingestion of food and/or drinking water contaminated with Vibrio cholerae. The disease is commonly found where there is poor sanitation and poor waste management. Outbreaks tend to occur in the aftermath of natural disasters or displacement situations where there is the collapse of infrastructure, as in the case of the 2022 floods in Pakistan, which brought about an exponential rise in cholera cases.

Cholera is most commonly spread through contaminated water sources, which is why the common query is: "How does cholera spread through water?" After ingestion, the bacterium infects the small intestine, producing toxins that lead to massive fluid loss and dehydration.

Recognizing the Symptoms

Cholera has an incubation period that is brief, between several hours and five days, and its symptoms can progress rapidly. The most typical symptoms are:

  • Severe, loose stools

  • Reinde

  • Muscle cramps

  • Low blood pressure

Both adults and children are at risk, with young children and the immunocompromised being at greatest risk for complications. If untreated, the disease can lead to 

Treatment and recovery

The mainstay of cholera management is rehydration. In the majority of patients, oral rehydration salts (ORS) are enough to restore fluid and electrolyte loss. For very severe disease, intravenous fluid and antibacterial drugs are needed. The data from the World Health Organization in 2023 project that in excess of 95% of cholera patients are cured through proper and timely hydration therapy.

Numerous inquiries arise as to whether cholera can be cured at home. Mild cases can actually be treated at home using ORS, as long as the patient has clean drinking water and caregivers are watching for the warning signs of dehydration. Medical care is, however, highly recommended should the symptoms get worseeath within hours in extreme cases.

Preventing Cholera in High-Risk Areas

Prevention of cholera remains the top global health priority as of 2025. Cholera prevention in low-income and disaster-stricken areas is reliant on the following key strategies:

  • Providing access to clean drinking water

  • Encourage good hand washing and food safety

  • Upgrading sanitation and waste management systems

  • Oral cholera vaccinations in the context of outbreaks or among at-risk populations

New vaccine campaigns with new-generation vaccines such as Euvichol-Plus, rolled out in various African nations in 2024, were found to be effective, lowering infection rates by as much as 40% during local epidemics.



Is Cholera still dangerous in 2025?

Cholera is still an ongoing concern, despite all the advances in public health. While uncommon in wealthier countries, it still reappears in weak contexts. In 2022, for example, there was a re-emergence of cholera in Haiti, many years after it had been declared to be under control. Cholera case studies from Africa and Asia, specifically from Mozambique, Nigeria, and Bangladesh, demonstrate how environmental causes and infrastructure deficiencies lead to ongoing transmission.

This brings us to the main question: what causes cholera to occur as an epidemic after flooding? Flooding tends to disrupt sanitation and contaminate drinking water to provide the dynamic conditions for transmission.

Cholera vs. Typhoid: A Comparison

Cholera is sometimes mistaken for other waterborne diseases, specifically typhoid fever. Cholera and typhoid fever are, though, quite different

  • Cholera, transmitted by Vibrio cholerae, results in acute diarrhea and dehydration.

  • Typhoid fever, which is produced by Salmonella typhi, is characterized by continued fever, weakness, and abdominal pain.


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